Post-inflammatory pigment spots: causes and treatment

Petele pigmentare postinflamatorii cauze si tratament

Post-inflammatory hyperpigmentation is a common dermatological problem, appearing as "marks" left on the skin after skin conditions or therapeutic interventions. Post-inflammatory pigment spots occur when the skin produces more melanin as part of its natural response to inflammation. Post-inflammatory pigment spots can affect both the epidermis and the dermis, are more common in people with darker skin, and can persist for months or even years in the absence of adequate treatment.

Below, we will explain what post-inflammatory pigment spots are, what their main causes are, and what treatment options can help fade them.

Pete pigmentare postinflamatorii

Table of Contents

What are post-inflammatory pigment spots?

Post-inflammatory hyperpigmentation or hypermelanosis is either the result of an overproduction of melanin or an abnormal deposition of pigment in the epidermis or dermis following inflammation.

During the inflammatory process, the chemical mediators that trigger inflammation also cause hypertrophy and activity of melanocytes. This increases melanin production in the epidermis. In deeper processes extending towards the dermis, basal keratinocytes are damaged and release large amounts of melanin, causing skin discoloration, which can be permanent.

Epidermal hyperpigmentation has a higher chance of resolution than hyperpigmentation at the dermal level.

What do post-inflammatory pigment spots look like?

Post-inflammatory pigment spots usually appear as discolored patches of skin. Called macules (irregular spots), they can be of different colors, depending on skin tone and the depth of discoloration. They appear in the area where the initial inflammation or lesion occurred.

Epidermal hyperpigmentation is light brown or dark brown and can persist for months or years, but tends to improve over time as the underlying inflammatory condition resolves.

Dermal hyperpigmentation is blue-gray and can be permanent.

Epidermal and dermal pigment spots can be present at the same time. If the inflammatory process is still active, erythematous papules and nodules may also be visible.

Post-inflammatory hyperpigmentation can occur in anyone, but it is more common in people with darker skin. It is also more intense and persists for a longer period than in people with lighter skin.

Post-inflammatory pigment spots: causes

Post-inflammatory pigment spots develop when a wound or irritation, a rash or a pimple causes skin inflammation.

When skin cells react to injury or irritation by producing additional melanin, the result is post-inflammatory hyperpigmentation.

The more inflamed an area is, the larger and darker the post-inflammatory pigment spot tends to be.

The most common causes of post-inflammatory pigment spots are acne, eczema and impetigo, but any type of inflammatory condition, trauma or skin irritation has the potential to cause hyperpigmentation. Other causes of post-inflammatory hyperpigmentation include:

  • sunburn;
  • insect bites;
  • allergic reactions;
  • infections;
  • psoriasis;
  • chemical peels;
  • dermabrasion;
  • laser procedures;
  • radiotherapy;
  • cryotherapy;
  • some medications (drug hypersensitivity reactions).

Post-inflammatory hyperpigmentation occurs following damage to the epidermis and/or dermis.

Post-inflammatory hyperpigmented spots are located at the site of the initial skin problem after it has healed.

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Post-inflammatory pigment spots: treatment

Identifying the source of inflammation and treating it can help accelerate healing and, consequently, reduce the severity of post-inflammatory hyperpigmentation. Hyperpigmented areas may also disappear on their own without treatment.

To help speed up the fading process of pigment spots, there are several types of treatments:

  • Topical application of products containing ingredients such as azelaic acid and hydroquinone, which help reduce melanin production.
  • Topical application of products containing ingredients such as retinoids, which help cell regeneration.
  • Topical application of products containing ingredients such as salicylic acid and glycolic acid, to remove skin cells with excess melanin.

? Try Ivatherm products for fading pigment spots:

Ivawhite Depigmenting Cream – increases brightness and smoothes sensitive skin with hyperpigmentation and dark spots. Reduces the number, size, and color intensity of lentigines (age spots), freckles, melasma, and post-inflammatory hyperpigmentation.

Ivawhite Intensive Depigmenting Serum – evens out and improves facial radiance and glow. Stimulates the disappearance of hyperpigmentation spots and prevents their recurrence. The serum has a dual mechanism of action on pigment spots: it reduces melanin production by inhibiting the enzymes involved in its formation and prevents melanin transfer to the upper layers of the skin.

Ivawhite Depigmenting Night Fluid with 5.5% Glycolic Acid – fades and eliminates hyperpigmentation spots by accelerating cell renewal and reduces pigment spots by inhibiting human tyrosinase and melanin production.

For deep post-inflammatory hyperpigmentation, chemical peels, laser treatments, and intense pulsed light (IPL) therapies can be performed. However, some more invasive methods for treating post-inflammatory pigment spots have the potential to cause irritation and even worsen the problem, so it is important to consult a dermatologist before any skin treatment and pay close attention to the skin's condition.

Whatever treatment option is chosen, it is important to remember that there is no quick fix for fading post-inflammatory pigment spots.

Pigment spots can disappear on their own, but it can take up to two years for this process to be complete. Both topical treatments and procedures performed in specialized clinics can help accelerate this process.

Epidermal post-inflammatory pigment spots can fade within 6 to 12 months or even longer. As for dermal post-inflammatory pigment spots, their fading can take years, and some of them never disappear.

Pigment spots can be concealed with makeup, but this is a temporary solution and does not help fade them. However, people with post-inflammatory hyperpigmentation who use makeup should choose products based on their skin type, ensuring they are non-comedogenic (do not clog pores), have long-lasting coverage, and are easy to apply daily.

Furthermore, because ultraviolet radiation can accentuate post-inflammatory hyperpigmentation and lead to the formation of other spots, specialists recommend avoiding sun exposure, especially on hot days, wearing protective clothing and accessories, and using a sunscreen with sun protection, with broad-spectrum coverage and an SPF of at least 30, every time we go outside.

In conclusion, post-inflammatory pigment spots are a common condition. They appear as a result of skin lesions or inflammation and can be a source of discomfort for many people. Fortunately, there are effective treatment options, but results take time to show.

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